Welcome to the Maretzky Lab!

About 80% of older adults have one chronic disease condition, and 50% have at least two such as cancer, cardiovascular diseases, progressive dementia, or connective tissue disorders. Our laboratory is investigating novel signaling pathways in chronic diseases, with a specific focus on inflammation-associated diseases.

Research Interests Include:

Studying the physiological relevance of the iRhom2/TACE signaling axis in the induction of inflammatory processes and characterizing the role of iRhom2/TACE in tissue degeneration and regeneration.

• Innate immune system
• Inflammation
• Host-Pathogen Interaction
• iRhoms in disease and development
• A Disintegrin and metalloprotease activation and regulation

Our laboratory uses a wide range of experimental techniques including molecular biology, protein chemistry, immunocytochemistry, cell culture, live-cell imaging, animal modeling , and computational systems biology analyses.